SLU-PP-332 5mg – [Exercise Mimic]

SLU-PP-332 5 mg — concise overview: benefits, mechanism, uses, dosing, and safety.

What it is

• SLU-PP-332 is a synthetic peptide and potent agonist of estrogen-related receptors (ERRs), especially ERRα. It is classified as an "exercise mimetic" because it reproduces many of the metabolic and cellular effects of aerobic exercise. A 5 mg vial refers to the total peptide before reconstitution; typical doses are in the microgram range.

Key benefits and uses

• Mimics aerobic exercise: Increases running endurance, VO₂ max, capillary density in muscle, and shifts muscle fibers toward oxidative (endurance) type, even without physical training 1 4 8.
• Supports fat loss and metabolic health: Reduces white adipose tissue, lowers fasting insulin and glucose, improves glucose tolerance, reverses hepatic steatosis (fatty liver), and reduces inflammation in liver and adipose tissue 1 4 5 7 11.
• Restores mitochondrial function: Increases mitochondrial density, enhances oxidative phosphorylation efficiency, boosts ATP production, reduces mitochondrial DNA damage, and upregulates mitophagy (removal of damaged mitochondria) 1 3 5.
• Improves insulin sensitivity: Beneficial for insulin resistance, metabolic syndrome, type 2 diabetes, and PCOS 1 5.
• Potential neuroprotective and anti-aging effects: Early research suggests possible benefits for cognitive health, neuroprotection, and age-related decline 9.

Mechanism of action

• SLU-PP-332 activates ERRα, which regulates genes involved in energy metabolism, mitochondrial biogenesis, and fat oxidation. This leads to increased energy expenditure, fatty acid oxidation, and improved insulin sensitivity 2 3 4 5 7.

Typical administration and dosing (non-prescriptive examples)

• Route: Oral (most common for SLU-PP-332, unlike many peptides), sublingual, or injectable forms may exist depending on formulation.
• Dosing: Typical research/clinical doses range from 200–800 mcg per day, divided into 2–3 doses. A 5 mg vial, after reconstitution, can provide multiple doses depending on dilution and protocol 5.
• Timing: Often taken 30 minutes before cardio or training for optimal effect, but can be taken at any time for metabolic support 5.