Vasoactive Intestinal Peptide (VIP) — 10 mg vial: concise benefits, uses, administration, dosing notes, and safety.
What it is
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VIP is a naturally occurring 28–amino‑acid neuropeptide with wide‑ranging roles: potent vasodilation, bronchodilation, modulation of gut motility and secretion, immunomodulation/anti‑inflammatory actions, and neuromodulation.
Reported/putative benefits & clinical uses
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Respiratory: bronchodilation and reduced airway inflammation — explored for asthma/COPD and pulmonary hypertension.
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Gastrointestinal: improves gut motility, secretions, and mucosal protection — researched for gastroparesis, inflammatory bowel disease, and functional GI disorders.
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Cardiovascular / microcirculation: vasodilation and improved microvascular blood flow; investigated for ischemic conditions and wound healing.
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Immunomodulation & anti‑inflammatory: reduces proinflammatory cytokine signaling in some models.
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Neuroprotective / cognitive: potential neurotrophic and neuroprotective effects (experimental).
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Sexual function: sometimes investigated for erectile dysfunction because of vasodilatory and neuronal effects.
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Wound healing & tissue repair: supports local perfusion and may aid healing in preclinical work.
Typical administration routes
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Subcutaneous or intramuscular injections (most common for off‑label/experimental use).
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Intranasal delivery has been studied for CNS/behavioral effects.
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IV infusion in specialized clinical research settings.
Dosing notes (10 mg vial context)
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“10 mg” refers to the total peptide in the vial before reconstitution; therapeutic doses are in the microgram range per administration.
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Common experimental doses vary widely by indication and route; microgram-level dosing (e.g., tens to hundreds of µg) given once or multiple times daily is typical in practice reports. Protocols differ substantially—follow a clinician’s protocol for reconstitution and per‑dose volumes.
Onset and expected effects
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Vasodilatory/bronchodilatory effects can be rapid (minutes to hours); other benefits (improved motility, tissue healing, neuro effects) evolve over days–weeks.

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