MOTs-c 10MG

MOTS‑c 10 mg — concise overview: what it is, reported benefits, mechanisms, typical uses, dosing/administration, safety, and practical notes.

What it is

• MOTS‑c (mitochondrial open‑reading‑frame of the 12S rRNA type-c) is a naturally occurring 16‑amino‑acid mitochondrial‑derived peptide that regulates metabolism and cellular stress responses. A 10 mg vial denotes total peptide before reconstitution; therapeutic doses are at the microgram–milligram scale depending on protocol.

Mechanism (key points)

• Modulates cellular metabolism by activating AMPK and improving insulin sensitivity and glucose uptake.
• Promotes mitochondrial homeostasis, fatty‑acid oxidation and energy expenditure.
• Enhances stress resistance, reduces oxidative stress and can influence nuclear gene expression related to metabolism.
• May stimulate pathways linked to longevity, exercise capacity and metabolic flexibility in preclinical models.

Reported / putative benefits & uses

• Improves insulin sensitivity and glucose metabolism — potential metabolic syndrome/diabetes support (investigational).
• Promotes fat loss and improved body composition by increasing fatty‑acid oxidation and energy expenditure.
• Enhances exercise capacity, recovery and endurance in animal studies; may support mitochondrial function in aging.
• May reduce inflammation and oxidative stress; possible cardiometabolic protective effects in preclinical work.
• Investigational use in age‑related metabolic decline, obesity, sarcopenic metabolic dysfunction and performance support.